Monday, 1 November 2010

Quantum politics.

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This post is about intellectual political conceptual expansion, the need to self evaluate at management level as that capacitate for others dependant, reliant and subservient to administration, cabinet and house. Much law that we have at this era accommodates for an expansion of economic principles on land acquainted with bond value to sociology conferring to cultural practice. It is inevitable science will come to answer many questions in space about things man has dreamed about upon this planet for thousands of years, perhaps hundreds of thousands, perhaps millions. To be sure, it is true to say that to cope, to be equipped, to be perpetrating equilibrium is and must be in all of our eyes an open debate maintaining equality from a cultural, scientific creed and religious perspective. When people have got their coats on and some people are drinking another glass of wine a singular journey is still occurring, it is good etiquette to say goodbye and to say farewell, it is terrific to receive friends and relatives, it is great to explore and come in from the tribulation of trial. Choosing the right way to do things is good for all... Heaven is our salvation upon which our toil speaks to our father in heaven and our mothers voice upon Earth...

Lord we give thanks that President Barack Obama has given us strength with his temperance and fortitude to end war with the land of Babylon, we pray for the men that gave their lives to their cause and that we trust it will not become ours, for peace is our liberty and let no man conspire to take it. Amen.

A prayer...

Psalm 137: By the waters of Babylon

1 By the waters of Babylon, there we sat down, yea, we wept, when we remembered Zion.
2 We hanged our harps upon the willows in the midst thereof.
3 For there they that carried us away captive required of us a song; and they that wasted us required of us mirth, saying, Sing us one of the songs of Zion.
4 How shall we sing the Lord'S song in a strange land?
5 If I forget thee, O Jerusalem, let my right hand forget her cunning.
6 If I do not remember thee, let my tongue cleave to the roof of my mouth; if I prefer not Jerusalem above my chief joy.
7 Remember, O Lord, the children of Edom in the day of Jerusalem; who said, Rase it, rase it, even to the foundation thereof.
8 O daughter of Babylon, who art to be destroyed; happy shall he be, that rewardeth thee as thou hast served us.
9 Happy shall he be, that taketh and dasheth thy little ones against the stones.

Psalm 137: By the waters of Babylon

Republica / Ready to go

Office swimmers

Olivia Newton John / Silvery rain

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Researchers Break Speed Barrier in Solving Important Class of Linear Systems

(Oct. 22, 2010) — Computer scientists at Carnegie Mellon University have devised an innovative and elegantly concise algorithm that can efficiently solve systems of linear equations that are critical to such important computer applications as image processing, logistics and scheduling problems, and recommendation systems.

The theoretical breakthrough by Professor Gary Miller, Systems Scientist Ioannis Koutis and Ph.D. student Richard Peng, all of Carnegie Mellon's Computer Science Department, has enormous practical potential. Linear systems are widely used to model real-world systems, such as transportation, energy, telecommunications and manufacturing that often may include millions, if not billions, of equations and variables.
Solving these linear systems can be time consuming on even the fastest computers and is an enduring computational problem that mathematicians have sweated for 2,000 years. The Carnegie Mellon team's new algorithm employs powerful new tools from graph theory, randomized algorithms and linear algebra that make stunning increases in speed possible.
The algorithm, which applies to an important class of problems known as symmetric diagonally dominant (SDD) systems, is so efficient that it may soon be possible for a desktop workstation to solve systems with a billion variables in just a few seconds.
The work will be presented at the annual IEEE Symposium on Foundations of Computer Science (FOCS 2010), Oct. 23-36 in Las Vegas.
A myriad of new applications have emerged in recent years for SDD systems. Recommendation systems, such as the one used by Netflix to suggest movies to customers, use SDD systems to compare the preferences of an individual to those of millions of other customers. In image processing, SDD systems are used to segment images into component pieces, such as earth, sky and objects like buildings, trees and people. "Denoising" images to bring out lettering and other details that otherwise might appear as a blur also make use of SDD systems.
A large class of logistics, scheduling and optimization problems can be formulated as maximum-flow problems, or "max flow," which calculate the maximum amount of materials, data packets or vehicles that can move through a network, be it a supply chain, a telecommunications network or a highway system. The current theoretically best max flow algorithm uses, at its core, an SDD solver.
SDD systems also are widely used in engineering, such as for computing heat flow in materials or the vibrational modes of objects with complex shapes, in machine learning, and in computer graphics and simulations.
"In our work at Microsoft on digital imaging, we use a variety of fast techniques for solving problems such as denoising, image blending and segmentation," said Richard Szeliski, leader of the Interactive Visual Media Group at Microsoft Research. "The fast SDD solvers developed by Koutis, Miller and Peng represent a real breakthrough in this domain, and I expect them to have a major impact on the work that we do."
Finding methods to quickly and accurately solve simultaneous equations is an age-old mathematical problem. A classic algorithm for solving linear systems, dubbed Gaussian elimination in modern times, was first published by Chinese mathematicians 2,000 years ago.
"The fact that you can couch the world in linear algebra is super powerful," Miller said. "But once you do that, you have to solve these linear systems and that's often not easy."
A number of SDD solvers have been developed, but they tend not to work across the broad class of SDD problems and are prone to failures. The randomized algorithm developed by Miller, Koutis and Peng, however, applies across the spectrum of SDD systems.
The team's approach to solving SDD systems is to first solve a simplified system that can be done rapidly and serve as a "preconditioner" to guide iterative steps to an ultimate solution. To construct the preconditioner, the team uses new ideas from spectral graph theory, such as spanning tree and random sampling.
The result is a significant decrease in computer run times. The Gaussian elimination algorithm runs in time proportional to s3, where s is the size of the SDD system as measured by the number of terms in the system, even when s is not much bigger the number of variables. The new algorithm, by comparison, has a run time of s[log(s)]2. That means, if s = 1 million, that the new algorithm run time would be about a billion times faster than Gaussian elimination.
Other algorithms are better than Gaussian elimination, such as one developed in 2006 by Daniel Spielman of Yale University and Miller's former student, Shang-Hua Teng of the University of Southern California, which runs in s[log(s)]25. But none promise the same speed as the one developed by the Carnegie Mellon team.
"The new linear system solver of Koutis, Miller and Peng is wonderful both for its speed and its simplicity," said Spielman, a professor of applied mathematics and computer science at Yale. "There is no other algorithm that runs at even close to this speed. In fact, it's impossible to design an algorithm that will be too much faster."

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Olivia Newton John / Deeper than the night

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RELEASE : 10-276

NASA'S Kepler Spacecraft Takes Pulse Of Distant Stars

WASHINGTON -- An international cadre of scientists that used data from NASA's Kepler spacecraft announced Tuesday the detection of stellar oscillations, or "starquakes," that yield new insights about the size, age and evolution of stars.

The results were presented at a news conference at Aarhus University in Denmark by scientists representing the Kepler Asteroseismic Science Consortium (KASC). The team studied thousands of stars observed by Kepler, releasing what amounts to a roster of some of humanity's most well-characterized stars.

Analysis of stellar oscillations is similar to how seismologists study earthquakes to probe the Earth's interior. This branch of science, called astroseismology, produces measurements of stars the Kepler science team is anxious to have.

"Using the unparalleled data provided by Kepler, KASC scientists are quite literally revolutionizing our understanding of stars and their structures," said Douglas Hudgins, Kepler Program Scientist at NASA Headquarters in Washington. "What's more, they are doing so at no cost to the American taxpayer. All the KASC scientists are supported by research funding from their home countries. It is a perfect illustration of the tremendous value that our international partners bring to NASA missions."

In the results presented Tuesday, one oscillating star took center stage: KIC 11026764 has the most accurately known properties of any star in the Kepler field. In fact, few stars in the universe are known to similar accuracy. At an age of 5.94 billion years, it has grown to a little over twice the diameter of the sun and will continue to do so as it transforms into a red giant. The oscillations reveal that this star is powered by hydrogen fusion in a thin shell around a helium-rich core.

"We are just about to enter a new area in stellar astrophysics," said Thomas Kallinger, lead author on a study of red giant stars and postdoctoral fellow at the Universities of British Columbia and Vienna. "Kepler provides us with data of such good quality that they will change our view of how stars work in detail."

KASC scientists also reported on the star RR Lyrae. It has been studied for more than 100 years as the first member of an important class of stars used to measure cosmological distances. The brightness, or light wave amplitude, of the star oscillates within a well-known period of about 13.5 hours. Yet during that period, other small cyclic changes in amplitude occur -- behavior known as the Blazhko effect.

The effect has puzzled astronomers for decades, but thanks to Kepler data, scientists may have a clue as to its origin. Kepler observations revealed an additional oscillation period that had never been previously detected. The oscillation occurs with a time scale twice as long as the 13.5-hour period. The Kepler data indicates the doubling is linked to the Blazhko effect.

"Kepler data ultimately will give us a better understanding of the future of our sun and the evolution of our galaxy as a whole," said Daniel Huber, lead author on one of the KASC studies.

Launched in March 2009, Kepler was designed to discover Earth-size planets orbiting other stars. The spacecraft uses a huge digital camera, known as a photometer, to continuously monitor the brightness of more than 150,000 stars in its field of view as it orbits around the sun. Kepler searches for distant worlds by looking for "transits," when a planet passes in front of a star, briefly causing it to dim. The amount of dimming reveals the size of the planet compared to the size of the star.

For more information about the findings by the KASC scientists, visit:

For more information about the Kepler mission, visit:

Olivia Newton John / A little more love

Olivia Newton John / If you love me {let me know}

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Positive Social Traits Trump Bad Health Habits, New Study Finds

(Oct. 22, 2010) — Many studies have documented the dangers of the traditional negative physical risk factors on health -- excessive smoking, drinking and being overweight. But far less research has focused on less-tangible, positive influences -- the protective role of psychological and social supports.

New research by Margie E. Lachman Ph.D. and Stefan Agrigoroaei Ph.D. of the Brandeis Psychology Department explores the psychological roots of health. Lachman is Director of the Lifespan Developmental Psychological Laboratory in the Department of Psychology, and Agrigoroaei is a postdoctoral researcher at the lab.
What Lachman and Agrigoroaei found in The Midlife in the U.S. (MIDUS) study, involving 3,626 adults aged 32 to 84 who were assessed over two periods about 10 years apart, was that with proper protective elements in place, declines in health could be delayed by up to a decade. Their findings indicate that specific psychological, social, and physical protective factors are associated with better health in later life.
The research identified physical exercise, social support and control beliefs, individually and in combination, as significant predictors of change in functional health, above and beyond the negative effects of the traditional risk factors.
"Control beliefs" refer to a person's sense of how much they can influence important life outcomes. Those who have a greater sense of control are more likely to engage in health-promoting behaviors, such as getting exercise and eating right. Suppotive social relationships can promote health by reducing stress and encouraging healthy behaviors.
The research is reported in the online journal PLoS ONE, published by the Public Library of Science.
The researchers note that the results are encouraging for the prospect of developing interventions to promote functional health, and for reducing public health costs for disabilities later in life.
This research was supported by The National Institute on Aging.

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It is my belief that mans inherent trait is to love, love being the essence that warms us, comforts us, shows us our path, our journey, but, I believe it is a journey that is the capacity which gives us our availability to life, as a person who listens to nature for lessons and advice, it is easy for me to be a servant of it's whim because it is our hunger which is the sustenance of life's story as we search for humble justification, our choices. To be with, is to be...

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Falling in Love Only Takes About a Fifth of a Second, Research Reveals

(Oct. 25, 2010) — A new meta-analysis study conducted by Syracuse University Professor Stephanie Ortigue reveals falling in love can elicit not only the same euphoric feeling as using cocaine, but also affects intellectual areas of the brain. Researchers also found falling in love only takes about a fifth of a second.

Results from Ortigue's team revealed when a person falls in love, 12 areas of the brain work in tandem to release euphoria-inducing chemicals such as dopamine, oxytocin, adrenaline and vasopression. The love feeling also affects sophisticated cognitive functions, such as mental representation, metaphors and body image.
The findings raise the question: "Does the heart fall in love, or the brain?"
"That's a tricky question always," says Ortigue. "I would say the brain, but the heart is also related because the complex concept of love is formed by both bottom-up and top-down processes from the brain to the heart and vice versa. For instance, activation in some parts of the brain can generate stimulations to the heart, butterflies in the stomach. Some symptoms we sometimes feel as a manifestation of the heart may sometimes be coming from the brain."
Ortigue is an assistant professor of psychology and an adjunct assistant professor of neurology, both in The College of Arts and Sciences at Syracuse University.
Other researchers also found blood levels of nerve growth factor, or NGF, also increased. Those levels were significantly higher in couples who had just fallen in love. This molecule involved plays an important role in the social chemistry of humans, or the phenomenon 'love at first sight.' "These results confirm love has a scientific basis," says Ortigue.
The findings have major implications for neuroscience and mental health research because when love doesn't work out, it can be a significant cause of emotional stress and depression. "It's another probe into the brain and into the mind of a patient," says Ortigue. "By understanding why they fall in love and why they are so heartbroken, they can use new therapies." By identifying the parts of the brain stimulated by love, doctors and therapists can better understand the pains of love-sick patients.
The study also shows different parts of the brain fall for love. For example, unconditional love, such as that between a mother and a child, is sparked by the common and different brain areas, including the middle of the brain. Passionate love is sparked by the reward part of the brain, and also associative cognitive brain areas that have higher-order cognitive functions, such as body image.
Ortigue and her team worked with a team from West Virginia University and a university hospital in Switzerland. The results of the study are published in the Journal of Sexual Medicine.
Ortigue worked on the love study with colleagues Francesco Bianchi-Demicheli (Geneva University Psychiatric Center, Switzerland), James Lewis (West Virginia University), Nisa Patel (graduate student in SU's College of Arts and Sciences) and Chris Frum (West Virginia University). Ortigue's follow-up study about the speed of love in the human brain is expected to be released soon.

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Dolly Parton / Jolene

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Olivia Newton John / Jolene

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Black and White: Marveling at a Brazil Where Racial Rules Are Learned Early in Life

I just returned from another wonderful trip to Brazil. I have been visiting that fascinating country for over 10 years, and on each of my visits I learn something new and different. On my latest visit one of the things I did was to spend time at a little fazenda. It wasn't really a farm; rather a small vineyard, vegetable garden, and flower garden nestled on the side of a rocky, mountainous area with a small stream running through it. There were two small houses - one for the owners, who live in a large city some 250 kilometers away, and the other one for the help - who care for the vineyard, gardens, chickens and a few horses.
I drove from the city to the fazenda with the owners. We were going to stay a couple of days, and enjoy a pick-nick with a few neighbors, friends and relatives. We turned off the hardtop road onto a very rough, dirt and boulder track. This track ended at the bottom of the steep hill at the farm.
After I explored the two gardens, marveling at a variety of healthy vegetables and colorful flowers - calla lilies and a beautiful red flower - which the owners took home with them on their return to the city (I grow both vegetables and flowers at my home in the United States, although on a smaller scale) and gazed at the dazzling swath of bright purple bougainvillea next to the house,
I joined the group for drinks and appetizers. After the appetizers and lively conversation, we settled into some great Minas Gerais country food. The group was made up of adults, with several college students (attending college activities in the nearby town), and two young girls.
One child was the daughter of the couple who care for the vineyard, garden and animals, and who prepared the wonderful food; the other was a relative of the owners. The domestic servants' daughter was about 10 years old; the other girl about 9 years old.
While socializing with the adults, I watched these two girls with interest. I am a teacher and child psychologist, so children's behaviors fascinate me. Further, it was more relaxing and enjoyable watching them play than trying to decipher the rapid Portuguese spoken all around me!
These two girls would disappear beyond the beautiful bougainvillea bush, down by the garden and the stream. They seemed to be having a great time in the wild brush and bamboo stands. They also rode a big, white horse, sitting bareback together and having a great time riding up by the vineyard. Occasionally they would dart into the house of the family who looked after the place, engaging in fantasy and housekeeping games girls this age seem to enjoy.
They were obviously very good friends, and enjoyed each other's company tremendously.
On a regular basis the girl related to the owners would join the adult group. She sat with us to listen to the latest gossip about friends and family; she also joined us to partake of the wonderful food prepared by her friend's mother. She would seamlessly slip between the world of the owners and the world of the domestic servants.
But her friend would never cross the line into the groups of adults in the main part of the house. She would occasionally come in through the back door to check in with her mother in the kitchen, but then she would retreat outside through the same door.
The family who cared for the farm and prepared the wonderful meal were what we in the Untied States would call African Americans (Afro Brazilians); the other girl, while much lighter than her friend, would probably be considered Hispanic in the U.S., based on her appearance (while labeled Moreno in Brazil), but she would also be considered white, since her family is European (Portuguese).
While I watched these two friends play, with the white girl moving between two worlds, but the black girl religiously keeping to her own, servant world, I marveled at a society that trained people so early in their lives and so effectively to play according to society's stick social rules.
[Here is where my Brazilian friends like to bring up our (U.S.) history of racism, and their belief in how racist a society the U.S. still is. It's not my intent to compare the two here. For what its worth, I have been married for over 30 years to an African American, and I have helped to raise and educate of four children of mixed-racial heritage in the U.S.].
On all my visits to Brazil, I have stayed with wonderful friends in their homes. Since most of my friends are typically from Brazil's middle and upper class, almost all of them had domestic servants - sometimes a woman; other times an entire family.
And, while these servants were of every shade of color, they invariably were a few shades darker than their bosses, who would not necessarily be considered white by U.S. standards. And when these domestic servants had children of a similar age to the owners, these children would be close friends, enjoying each other's company with little concern for social class, as children do.
While I have never seen servants mistreated, I am constantly fascinated by the relationship between the employer and employee, and the fact that a country attempting to be a world leader has such a deeply institutionalized, inequitable and racists system.
One particular example stands out in my mind. A 16-year-old girl was the servant for a single, professional woman (a teacher) and her two adult children - one with a child. She would do the laundry, cook meals, make the beds, and clean the rooms of these two adults. Yes, the beds of the grown children!
My own children were doing their own laundry by about 11-years-old, and, while they did not always make their beds, no one would do it for them. Once their rooms got too messy to tolerate, they would clean them up themselves.
Sure we have nannies in the United States. Many people also make a good living cleaning houses. And there are after-school and weekend programs, along with an entire array of sports options, available for children. But it's different.
Middle-class families in America cannot afford nannies and servants; occasionally they might hire someone to help clean their home. And these service people are not second-class citizens - they are themselves part of middle-class America (maids in hotels and motels are a different matter).
I know Lula's government has increased the minimum wage, pays parents when their children attend school, created new universities and expanded old ones (although, given the sorry state of public schools, I am not sure where the new students will come from - see Improving Brazil's Public Schools: Nine Recommendations, in - ), and is investing in preschool programs throughout the country.
But I wonder how these changes will impact this highly institutionalized, totally inequitable system, which seems so permanently embedded within contemporary Brazilian culture.
And I wonder what the future holds for the little black girl I saw ridging a beautiful white horse, and playing hide-and-seek with her friend under an expansive bougainvillea bush and behind the bamboo stands.
Francis Wardle has a Ph.D. in Education (University of Kansas). He has been a Head Start director, education director of Children's World Learning Centers (a national childcare and education corporation), a teacher, and a program director for Big Brothers & Sisters. Currently Dr. Wardle teaches for the University of Phoenix (online) and Red Rocks Community College (Denver). He has published four college textbooks and over 300 articles in a variety of educational magazines and journals.

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Olivia Newton John / I honestly love you

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Olivia Newton John / Totally hot

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Looking around the world, I see a lot of happy people, actually, thats all I want to see, not because i'm ignorant, but, i realise that many shy people become unhappy, it is probably something to do with social circles where people are extraordinarily outrageous with trend and the latest fashion garment. It is something that could be construed as an artistic creativeness that people are really fond of, but, it is my belief that some people want to remain culturally complete in their era, and thus, the neccessity to consider the implications of social tides instigated by population booms, exploration, and cultural fantasy presents the need for a centrifugal political ''updating''. As we have witnessed the previous historical text evidence, people favour regional climates that offer, warmth, some offer a multitude of regionics that people like to intrgrate into there roster. It is something that I belive the next generation of space science and engineering will bring offer.

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It is my belief that men have opportunities to do what is right for the people of the land when they are voted to do so, to achieve those necessities given the opportunity of solutions, it is my belief that voting systems will become more knowledgeable and thus the credence of their virtue will become more apparant.

Clannad / Of this land

Clannad / Something to believe in

Clannad / In a life time

It is a learning process that men and women will want to experience themselves, in a universe where men will be galactic travellers hopefully for pacifist exploration...

Leaders??? They come and go, love, bonding, fruition, they are won and lost, but, it is my solomn hope that our exploits as humans will be committed among perimeters of law and order and justice based upon intelligent legal concioussness. Ignorance is a sin under the circumstances for leaders to carry a lie on to any table with a smile. Democracy has it's commune, I prey it tells true for the people are listening in the heavens.

Kansas / Carry on my wayward son

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Cupid's Arrow May Cause More Than Just Sparks To Fly This Valentine's Day

(Feb. 14, 2009) — Getting struck by Cupid's arrow may very well take your breath away and make your heart go pitter patter this Valentine's Day, reports Loyola University Health System love guru Domeena Renshaw, MD.

"Falling in love causes our body to release a flood of feel-good chemicals that trigger specific physical reactions," said Domeena Renshaw, MD, author, Seven Weeks to Better Sex, director, Loyola University Health System Sex Clinic and professor, Department of Psychiatry and Behavioral Neurosciences, Loyola University Chicago Stritch School of Medicine. "This internal elixir of love is responsible for making our cheeks flush, our palms sweat and our hearts race."
Levels of these substances, which include dopamine, adrenaline and norepinephrine, increase when two people fall in love. Dopamine creates feelings of euphoria while adrenaline and norepinephrine are responsible for the pitter patter of the heart, restlessness and overall preoccupation that go along with experiencing love.
MRI scans indicate that love lights up the pleasure center of the brain. When we fall in love, blood flow increases in this area, which is the same part of the brain responsible for drug addiction and obsessive compulsive disorders.
"Love lowers serotonin levels, which is common in people with obsessive compulsive disorders," said Renshaw. "This may explain why we concentrate on little other than our partner during the early stages of a relationship."
Renshaw cautions that these physical responses to love may work to our disadvantage.
"The phrase 'love is blind' is a valid notion, because we tend to idealize our partner and see only things that we want to see in the early stages of the relationship," said Renshaw. "Outsiders have a much more objective and rational perspective on the partnership than the two people involved do."
There are three phases of love, which include lust, attraction and attachment. Lust is a hormone-driven phase where we experience desire. Blood flow to the pleasure center of the brain happens during the attraction phase, when we feel an overwhelming fixation with our partner. This behavior fades during the attachment phase, when the body develops a tolerance to the pleasure stimulants. Endorphins and hormones vasopressin and oxytocin also flood the body at this point creating an overall sense of well-being and security that is conducive to a lasting relationship.

Olivia Newton John / Please mister please

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Olivia Newton John / Have you ever been mellow

Molecular Guardian of Cell's RNA Identified

(Oct. 26, 2010) — When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins -- they have to be processed first. One of those processes is called splicing, a mechanism by which non-coding gene sequences are removed and the remaining protein-coding sequences are joined together to form a final, mature messenger RNA (mRNA), which contains the recipe for making a protein.

For years, researchers have understood the roles played by the molecular machines that carry out the splicing process. But, as it turns out, one of those familiar components plays a new, and altogether unexpected role.

As senior author Gideon Dreyfuss, PhD, the Isaac Norris Professor of Biochemistry and Biophysics at the University of Pennsylvania School of Medicine and colleagues report in Nature, one of the splicing machinery's components called U1 has a second, equally important role in gene expression: To enable gene sequences to be read out into their RNA transcripts in their entirety, rather than have that process prematurely stopped. Dreyfuss is also a Howard Hughes Medical Institute Investigator.

The researchers revealed an unexpected function for U1 in protecting mRNA transcripts from premature termination in addition to and independent of its role in splicing.

As Dreyfuss puts it, "U1 is a guardian of the transcriptome." The transcriptome is the set of all RNA molecules in one cell.

U1 is one of a collection of RNA-protein complexes, called snRNPs, that recognize splicing junctions, excise non-coding gene sequences called introns, and join the remaining coding sequences called exons together. The Dreyfuss team previously showed that loss of SMN, a protein that helps assemble snRNPs and is deficient in individuals with the common neurodegenerative disease spinal muscular atrophy (SMA), results in altered snRNP levels and abnormal splicing.

SMN deficiency affects all snRNPs to one degree or another. The Dreyfuss team wanted to find out what would happen if just one snRNP was missing. They started with U1.

The team's expectation was that they would detect an increase in unspliced RNA transcripts, and indeed they saw evidence of that. But, to their surprise, the majority of the genes produced a very different and striking result. Their transcripts terminated prematurely and abruptly, generally within a relatively short distance from the transcription start site of the gene.

When they sequenced the ends of the resulting truncated RNAs, they found that they had been prematurely cleaved and tagged with a long string of nucleotide building blocks called adenine. This string is a hallmark of a process called cleavage-and-polyadenylation, which normally occurs at the end of a gene's RNA transcript. The lack of U1 was causing the cleavage/polyadenylation machinery to kick into gear early.

The implication, Dreyfuss says, is that U1's normal role, in addition to splicing, is to keep the cleavage/polyadenylation machinery in check until the RNA polymerase enzyme that synthesizes the transcript reaches its finish line. The researchers propose a model in which U1 binds throughout the nascent RNA transcripts, stymieing the cleavage/polyadenylation machinery that tags along with the moving polymerase complex. This in turn protects the many potential polyadenylation signals encountered along the way, and could explain the relative abundance of U1 in cells compared to other snRNPs. The additional U1 corresponds to the greater amount needed for its additional function.

"The transcripts are under constant threat from the cleavage/polyadenylation machinery," Dreyfuss explains. "This machinery doesn't patiently wait for the transcript to reach the end of the gene; rather, the nascent RNA transcripts are subject to becoming attacked by this machinery. It's a constant danger they face, and the U1 snRNP suppresses it."

It is, he says, "a novel role" for U1, and a critical component for correctly making mRNA. "It is essential for the integrity of the transcriptome, the landscape of all mRNA molecules in the cell," he concludes.

Other coauthors on the paper include Penn researchers Daisuke Kaida, Michael Berg, Ihab Younis, Mumtaz Kasim, Larry Singh, and Lili Wan. The research was funded by the Association Française Contre les Myopathies and the Howard Hughes Medical Institute.

Our evolution path will vary according to our leadership political consensus voting options, I believe it will become more important and fundamentally imperitive that we recognise the expansion into space regarding our ability to correspond with expansion and contracting demographics according to safety standards and our knowledge of conditioning. I have spent a lot of time in libraries researching and truthfully, the library is one of my favourite places in the world, I have seen a lot of scholarly work vindicate our research on this planet and myself hope to add much to our scientific knowledge for our safe journey and passage into life and it's continuing myriad. Time is a teller and it is the wise who live among time and become it's servant, we name a servant of time a culture, it is a wonderous thing to watch, learn from and experience different cultures among their habitats, this will continue into space and hopefully we work to maintain everything that we have learnt about regions cultures so that many thousands, perhaps millions and billions of years into the future we have them as tresure troves of resource for, holidays, for re and de acclimatising, for lessons, and for learning love, virtue and the essence of all things humble, gracious and self centering and among the future most importantly inbreeding and outbreeding.

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Tracking Golden Eagles by Satellite; Impact of Large-Scale Wind Farms Studied

(Oct. 25, 2010) — Large-scale wind farm establishment may have a negative effect on Sweden's golden eagles. In a unique project in northern Sweden, scientists at the Swedish University of Agricultural Sciences (SLU) are trapping adult golden eagles and fitting them with satellite transmitters.

The satellite transmitters emit a signal once an hour during the daytime. These signals provide the scientists with a picture of how the birds use the landscape.
"Hopefully we can identify the golden eagles' favourite habitats. When we've done that we can see where wind farms can be established without disturbing the eagles," says project manager Tim Hipkiss at SLU's Department of Wildlife, Fish and Environmental Studies.
The potential risks with wind farms are that the birds collide with the rotor blades and lose valuable hunting habitat.
Up to now the scientists have fitted transmitters on to six eagles. The goal is twenty adult eagles from ten territories, five where wind farms are planned and five without wind farms (reference areas). The project is estimated to run for long enough for the scientists to monitor the eagles during wind farm establishment. Most of the sites are in Västerbotten county in northern Sweden.
"Trapping adult golden eagles alive has never been done before in Sweden, and probably nowhere else in Europe. This is unique, and most people thought we wouldn't succeed," says Tim Hipkiss.
SLU's scientists have acquired the assistance of some of the world's leading experts in this field, from USA, where it is more common to trap birds of prey as part of conservation projects.
The trapping is carried out by the scientists placing out carrion at feeding sites a few weeks in advance, so that the eagles get used to finding food there. After this the American experts conceal a net trap and erect a hide a small distance from the net.
"Then you just have to wait patiently in the hide. When the eagle lands on the food, the person in the hide releases the net. With the help of an assistant waiting nearby the eagle is then dealt with," says Tim Hipkiss.
Fitting the satellite transmitter takes around half an hour, and it is important those involved know what they are doing. The eagles can weigh up to six kilos and wield dangerous claws. By weighing the bird and measuring its wing-length, you can tell if it is a male or a female (females are larger). The transmitter sits in place like a comfortable backpack.
Tim Hipkiss says that the birds have no problems flying with these transmitters. The adult birds fly several kilometres per day. Last summer, the scientists also fitted five juvenile golden eagles with transmitters, and have since monitored them for several months.
"The juveniles fly as they should, and some have already flown to new hunting grounds tens of kilometres away. Thanks to the transmitters we can find the birds if any of them have any problems, for example have not moved for several days," says Tim Hipkiss.
The satellite transmitters will provide information on how far the eagles fly and how they move about their territories before and after wind farm establishment. The scientists have already observed that the eagles fly further than previously thought.
"It's really great to see that this works. So far the project looks successful," says Tim Hipkiss.
The project "Effects of wind farms on the habitat use and reproductive success of golden eagles" is financed by the Swedish Energy Agency (Vindval programme) and the power companies Vattenfall and Statkraft.

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Spray on DNA mist used to catch criminals

Imagine getting sprayed with DNA when you walked into a private business. If that sounds crazy, you must not be living in the Netherlands, where spray-on DNA mist is an increasingly popular form of theft prevention. The system uses newly created synthetic DNA, and probably wouldn't work with 419-million year-old DNA.
The DNA sprayer goes above a private business's entrance, usually accompanied by an ominous sign that says something like, "You Steal, You’re Marked.”
The idea is that if someone is robbing a private business, an employee would activate the DNA sprayer without attracting the thief's attention, much like how you would active a silent alarm. The invisible spray permeates the air and settles onto the thief without his knowing it. The local police department is automatically alerted to a possible crime in progress.
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Visible only under ultraviolet light, the mist carries synthetic DNA markers unique to the location, allowing the police to match the thief with the place burgled. The DNA mist is imperceptible to those who come into contact with it. The manager of one business that now uses the technology told the New York Times, “You don’t smell it; you don’t see it; nobody knows it’s there.”
The technology is more about keeping potential thieves at bay, rather than actually capturing a burglar once the crime has been committed. At least, that's what one company behind DNA mist technology is saying.

Donald van der Laan's company, the Rhine Group, distributes this DNA spray to Dutch businesses. He says the devices aren't supposed to capture crooks so much as they are supposed to scare away potential thieves. As he told the New York Times, “The whole thing is prevention, not about recovering stolen goods or capturing criminals."
The company claims to have helped drastically reduce the crime in the areas where the technology has been deployed. Before you get too excited, however, the company hasn't released any figures to prove that assertion. The local police department says it hasn't made any arrests using the DNA spray, even though several crimes have occurred.

This is the end of this post, I hope you give these songs the opportunity of feeling...
The closer I get to realising my dreams and ambitions the more I feel like the feeling these people bring...

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Sugarhill gang / Rappers delight

Gregory Isaacs / My religion

Fatback band / I found lovin

WWO-W wyjatkowych okolicznosciach...

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Special note:

Sending full and total support to President Barack Obama for his unparalled humanitarian work around the world of this era's presidencies.

No Doubt / Don't speak

Bonnie Tyler / Total eclipse of the heart

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